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A Molecular Mechanism for Glaucoma: Endoplasmic Reticulum Stress and the Unfolded Protein Response
Primary open angle glaucoma (POAG) is a common late-onset neurodegenerative disease. Ocular hypertension represents a major risk factor, but POAG etiology remains poorly understood. Some cases of early-onset congenital glaucoma and adult POAG are linked to mutations in myocilin, a secreted protein o...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795998/ https://ncbi.nlm.nih.gov/pubmed/23876925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2013.06.005 |
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