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miRISC recruits decapping factors to miRNA targets to enhance their degradation
MicroRNA (miRNA)-induced silencing complexes (miRISCs) repress translation and promote degradation of miRNA targets. Target degradation occurs through the 5′-to-3′ messenger RNA (mRNA) decay pathway, wherein, after shortening of the mRNA poly(A) tail, the removal of the 5′ cap structure by decapping...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3794582/ https://ncbi.nlm.nih.gov/pubmed/23863838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt619 |
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