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A Molecular Link between miRISCs and Deadenylases Provides New Insight into the Mechanism of Gene Silencing by MicroRNAs

MicroRNAs (miRNAs) are a large family of endogenous noncoding RNAs that, together with the Argonaute family of proteins (AGOs), silence the expression of complementary mRNA targets posttranscriptionally. Perfectly complementary targets are cleaved within the base-paired region by catalytically activ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Braun, Joerg E., Huntzinger, Eric, Izaurralde, Elisa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504443/
https://ncbi.nlm.nih.gov/pubmed/23209154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012328
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