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HPat provides a link between deadenylation and decapping in metazoa

Decapping of eukaryotic messenger RNAs (mRNAs) occurs after they have undergone deadenylation, but how these processes are coordinated is poorly understood. In this study, we report that Drosophila melanogaster HPat (homologue of Pat1), a conserved decapping activator, interacts with additional deca...

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Autores principales: Haas, Gabrielle, Braun, Joerg E., Igreja, Cátia, Tritschler, Felix, Nishihara, Tadashi, Izaurralde, Elisa
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856893/
https://ncbi.nlm.nih.gov/pubmed/20404111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200910141
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