Solution NMR Structure and Histone Binding of the PHD Domain of Human MLL5

Mixed Lineage Leukemia 5 (MLL5) is a histone methyltransferase that plays a key role in hematopoiesis, spermatogenesis and cell cycle progression. In addition to its catalytic domain, MLL5 contains a PHD finger domain, a protein module that is often involved in binding to the N-terminus of histone H...

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Detalhes bibliográficos
Main Authors: Lemak, Alexander, Yee, Adelinda, Wu, Hong, Yap, Damian, Zeng, Hong, Dombrovski, Ludmila, Houliston, Scott, Aparicio, Samuel, Arrowsmith, Cheryl H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793974/
https://ncbi.nlm.nih.gov/pubmed/24130829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077020
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