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HSP70 and constitutively active HSF1 mediates protection against CDCrel-1-mediated toxicity
Defects in cellular quality control mechanisms are thought to contribute to Parkinson’s disease (PD) neuropathology. Overexpressing heat shock proteins (HSP) may be a powerful therapeutic strategy for PD as it boosts the ability of the cell to eliminate unwanted proteins. We investigated the neuropr...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3793395/ https://ncbi.nlm.nih.gov/pubmed/18398426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.68 |
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