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Increased HSF activation in muscles with a high constitutive Hsp70 expression

Stress-induced transcriptional regulation of the Hsps is mediated by trimerization and binding of a pre-existing heat shock transcription factor (HSF1) to a specific DNA sequence located in the 5′ region of hsp genes, known as the heat shock element. Hsp70 has been implicated in regulating the activ...

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Autori principali: Locke, Marius, Tanguay, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Stress Society International 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC248479/
https://ncbi.nlm.nih.gov/pubmed/9222604
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