Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways

The ability to maintain proper airway surface liquid (ASL) volume homeostasis is vital for mucus hydration and clearance, which are essential aspects of the mammalian lung’s innate defense system. In cystic fibrosis (CF), one of the most common life-threatening genetic disorders, ASL dehydration lea...

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Detalhes bibliográficos
Main Authors: Garland, Alaina L., Walton, William G., Coakley, Raymond D., Tan, Chong D., Gilmore, Rodney C., Hobbs, Carey A., Tripathy, Ashutosh, Clunes, Lucy A., Bencharit, Sompop, Stutts, M. Jackson, Betts, Laurie, Redinbo, Matthew R., Tarran, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791714/
https://ncbi.nlm.nih.gov/pubmed/24043776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311999110
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