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SPLUNC1 Degradation by the Cystic Fibrosis Mucosal Environment Drives Airway Surface Liquid Dehydration
Cystic fibrosis (CF) is a multi-organ disease caused by mutations in the cystic fibrosis transmembrane regulator (CFTR) gene that leads to diminished transepithelial anion transport. CF lungs are characterised by airway surface liquid (ASL) dehydration, chronic infection/inflammation and neutrophili...
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| Publicado no: | Eur Respir J |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547379/ https://ncbi.nlm.nih.gov/pubmed/30190268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00668-2018 |
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