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Cigarette smoke modifies and inactivates SPLUNC1, leading to airway dehydration

Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity and mortality worldwide. Cigarette smoke (CS) exposure, a major cause of COPD, dysregulates airway epithelial ion transport and diminishes airway surface liquid (ASL) volume. Short palate lung and nasal epithelial clone 1 (...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Moore, Patrick J., Reidel, Boris, Ghosh, Arunava, Sesma, Juliana, Kesimer, Mehmet, Tarran, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219833/
https://ncbi.nlm.nih.gov/pubmed/29890087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800345R
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