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Phytoestrogen Genistein Up-Regulates Endothelial Nitric Oxide Synthase Expression Via Activation of cAMP Response Element-Binding Protein in Human Aortic Endothelial Cells

We previously reported that genistein, a phytoestrogen, up-regulates endothelial nitric oxide synthase (eNOS) and prevents hypertension in rats that are independent of estrogen signaling machinery. However, how genistein regulates eNOS expression is unknown. In the present study, we show that genist...

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書誌詳細
主要な著者: Si, Hongwei, Yu, Jie, Jiang, Hongling, Lum, Hazel, Liu, Dongmin
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791435/
https://ncbi.nlm.nih.gov/pubmed/22669896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1076
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