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Phytoestrogen Genistein Up-Regulates Endothelial Nitric Oxide Synthase Expression Via Activation of cAMP Response Element-Binding Protein in Human Aortic Endothelial Cells

We previously reported that genistein, a phytoestrogen, up-regulates endothelial nitric oxide synthase (eNOS) and prevents hypertension in rats that are independent of estrogen signaling machinery. However, how genistein regulates eNOS expression is unknown. In the present study, we show that genist...

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書目詳細資料
Main Authors: Si, Hongwei, Yu, Jie, Jiang, Hongling, Lum, Hazel, Liu, Dongmin
格式: Artigo
語言:Inglês
出版: Endocrine Society 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791435/
https://ncbi.nlm.nih.gov/pubmed/22669896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1076
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