Genistein Prevents Hyperglycemia-Induced Monocyte Adhesion to Human Aortic Endothelial Cells through Preservation of the cAMP Signaling Pathway and Ameliorates Vascular Inflammation in Obese Diabetic Mice(2)

Hyperglycemia-induced vascular inflammation resulting in the enhanced monocyte-endothelial cell (EC) interaction is the key event in the pathogenesis of atherosclerosis in diabetes. Here, we investigated the effect of isoflavone genistein on hyperglycemia-stimulated vascular inflammation. Human aort...

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Detalhes bibliográficos
Main Authors: Babu, Pon Velayutham Anandh, Si, Hongwei, Fu, Zhuo, Zhen, Wei, Liu, Dongmin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2012
Assuntos:
Nutrition and Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3301991/
https://ncbi.nlm.nih.gov/pubmed/22399524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.111.152322
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