Loading...

Phytoestrogen Genistein Protects Against Endothelial Barrier Dysfunction in Vascular Endothelial Cells Through PKA-Mediated Suppression of RhoA Signaling

The soy-derived phytoestrogen genistein has received attention for its potential to improve vascular function, but its mechanism remains unclear. Here, we report that genistein at physiologically relevant concentrations (0.1–10 μM) significantly inhibited thrombin-induced increase in endothelial mon...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Jia, Zhenquan, Zhen, Wei, Velayutham Anandh Babu, Pon, Liu, Dongmin
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548180/
https://ncbi.nlm.nih.gov/pubmed/23254196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1774
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!