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Soy phytoestrogen genistein up-regulates the expression of human endothelial nitric oxide synthase and lowers blood pressure in spontaneously hypertensive rats

Genistein, a soy phytoestrogen, may improve vascular function but the mechanism of this effect is unclear. Endothelial-derived nitric oxide (NO) is a key regulator of vascular tone and atherogenesis. Previous studies have established that estrogen can act directly on vascular endothelial cells to en...

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Detalhes bibliográficos
Main Authors: Si, Hongwei, Liu, Dongmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2263007/
https://ncbi.nlm.nih.gov/pubmed/18203895
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