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Immuno- and Constitutive Proteasomes Do Not Differ in Their Abilities to Degrade Ubiquitinated Proteins

Immunoproteasomes are alternative forms of proteasomes that have an enhanced ability to generate antigenic peptides. Recently, Seifert and colleagues reported surprising observations concerning the functions of immunoproteasomes and cellular responses to interferon-γ: (1) that immunoproteasomes degr...

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Главные авторы: Nathan, James A., Spinnenhirn, Valentina, Schmidtke, Gunter, Basler, Michael, Groettrup, Marcus, Goldberg, Alfred L.
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791394/
https://ncbi.nlm.nih.gov/pubmed/23452861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.01.037
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