Activated Cyclin-Dependent Kinase 5 Promotes Microglial Phagocytosis of Fibrillar β-Amyloid by Up-regulating Lipoprotein Lipase Expression

Amyloid plaques are crucial for the pathogenesis of Alzheimer disease (AD). Phagocytosis of fibrillar β-amyloid (Aβ) by activated microglia is essential for Aβ clearance in Alzheimer disease. However, the mechanism underlying Aβ clearance in the microglia remains unclear. In this study, we performed...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ma, Yuanhui, Bao, Jintao, Zhao, Xuyang, Shen, Hongyan, Lv, Junniao, Ma, Shuaipeng, Zhang, Xuefei, Li, Zeyang, Wang, Shuxin, Wang, Qingsong, Ji, Jianguo
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Biochemistry and Molecular Biology 2013
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790294/
https://ncbi.nlm.nih.gov/pubmed/23816988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.026864
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