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Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation

Microglia become increasingly dysfunctional with aging and contribute to the onset of neurodegenerative disease (NDs) through defective phagocytosis, attenuated cholesterol efflux, and excessive secretion of pro-inflammatory cytokines. Dysfunctional microglia also accumulate lipid droplets (LDs); ho...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Loving, Bailey A., Tang, Maoping, Neal, Mikaela C., Gorkhali, Sachi, Murphy, Robert, Eckel, Robert H., Bruce, Kimberley D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909280/
https://ncbi.nlm.nih.gov/pubmed/33498265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020198
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