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Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation

Microglia become increasingly dysfunctional with aging and contribute to the onset of neurodegenerative disease (NDs) through defective phagocytosis, attenuated cholesterol efflux, and excessive secretion of pro-inflammatory cytokines. Dysfunctional microglia also accumulate lipid droplets (LDs); ho...

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Pubblicato in:Cells
Autori principali: Loving, Bailey A., Tang, Maoping, Neal, Mikaela C., Gorkhali, Sachi, Murphy, Robert, Eckel, Robert H., Bruce, Kimberley D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909280/
https://ncbi.nlm.nih.gov/pubmed/33498265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020198
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