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Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation

Microglia become increasingly dysfunctional with aging and contribute to the onset of neurodegenerative disease (NDs) through defective phagocytosis, attenuated cholesterol efflux, and excessive secretion of pro-inflammatory cytokines. Dysfunctional microglia also accumulate lipid droplets (LDs); ho...

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Publicado en:Cells
Autores principales: Loving, Bailey A., Tang, Maoping, Neal, Mikaela C., Gorkhali, Sachi, Murphy, Robert, Eckel, Robert H., Bruce, Kimberley D.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7909280/
https://ncbi.nlm.nih.gov/pubmed/33498265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020198
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