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The ribosome triggers the stringent response by RelA via a highly distorted tRNA
The bacterial stringent response links nutrient starvation with the transcriptional control of genes. This process is initiated by the stringent factor RelA, which senses the presence of deacylated tRNA in the ribosome as a symptom of amino-acid starvation to synthesize the alarmone (p)ppGpp. Here w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3790049/ https://ncbi.nlm.nih.gov/pubmed/23877429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.106 |
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