cAMP Response Element-binding Protein (CREB) and Nuclear Factor κB Mediate the Tamoxifen-induced Up-regulation of Glutamate Transporter 1 (GLT-1) in Rat Astrocytes

Tamoxifen (TX), a selective estrogen receptor modulator, exerts antagonistic effects on breast tissue and is used to treat breast cancer. Recent evidence also suggests that it may act as an agonist in brain tissue. We reported previously that TX enhanced the expression and function of glutamate tran...

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Detalhes bibliográficos
Main Authors: Karki, Pratap, Webb, Anton, Smith, Keisha, Lee, Kyuwon, Son, Deok-Soo, Aschner, Michael, Lee, Eunsook
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789995/
https://ncbi.nlm.nih.gov/pubmed/23955341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.483826
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