Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes

Glutamate transporter-1 (GLT-1) plays a central role in preventing excitotoxicity by removing excess glutamate from the synaptic clefts. 17β-estradiol (E2) and tamoxifen (TX), a selective estrogen receptor modulator (SERM), afford neuroprotection in a range of experimental models. However, the mecha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lee, Eunsook, Sidoryk-Węgrzynowicz, Marta, Yin, Zhaobao, Webb, Anton, Son, Deok-Soo, Aschner, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353324/
https://ncbi.nlm.nih.gov/pubmed/22488924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22329
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