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Estrogen and tamoxifen reverse manganese–induced glutamate transporter impairment in astrocytes

Chronic exposure to manganese (Mn) can cause manganism, a neurodegenerative disorder similar to Parkinson's disease. The toxicity of Mn includes impairment of astrocytic glutamate transporters. 17β-Estradiol (E2) has been shown to be neuroprotective in various neurodegenerative diseases includi...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Eun-Sook Y., Sidoryk, Marta, Jiang, Haiyan, Yin, Zhaobao, Aschner, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920654/
https://ncbi.nlm.nih.gov/pubmed/19453300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06105.x
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