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Animal Toxicity of Hairpin Pyrrole-Imidazole Polyamides Varies with the Turn Unit
[Image: see text] A hairpin pyrrole-imidazole polyamide (1) targeted to the androgen receptor consensus half-site was found to exert antitumor effects against prostate cancer xenografts. A previous animal study showed that 1, which has a chiral amine at the α-position of the γ-aminobutyric acid turn...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American
Chemical Society
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3788622/ https://ncbi.nlm.nih.gov/pubmed/24015881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401100s |
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