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Intracerebroventricular Administration of Amyloid β-protein Oligomers Selectively Increases Dorsal Hippocampal Dialysate Glutamate Levels in the Awake Rat

Extensive evidence supports an important role for soluble oligomers of the amyloid β-protein (Aβ) in Alzheimer's Disease pathogenesis. In the present study we combined intracerebroventricular (icv) injections with brain microdialysis technology in the fully conscious rat to assess the effects o...

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Detalhes bibliográficos
Main Authors: O'Shea, Sean D., Smith, Imelda M., McCabe, Olive M., Cronin, Michelle M., Walsh, Dominic M., O'Connor, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787453/
https://ncbi.nlm.nih.gov/pubmed/27873937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s8117428
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