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A Specific ELISA for Measuring Amyloid β-Protein Oligomers in Human Plasma and the Brains of Alzheimer Patients

1. OBJECTIVE: A new ELISA specific for oligomeric assemblies of amyloid β protein (oAβ) was developed to examine in vivo levels of oAβ vs. monomeric Aβ in sporadic and familial Alzheimer disease (AD) plasma and brain tissue. 2. DESIGN: To establish the oAβ ELISA, the same N-terminal Aβ antibody was...

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Detalhes bibliográficos
Main Authors: Xia, Weiming, Yang, Ting, Smith, Imelda M., Shen, Yong, Walsh, Dominic M., Selkoe, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618974/
https://ncbi.nlm.nih.gov/pubmed/19204155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2008.565
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