Aβ oligomers inhibit synapse remodelling necessary for memory consolidation

Extensive research has implicated the amyloid-β protein (Aβ) in the aetiology of Alzheimer’s disease (AD). This protein has been shown to produce memory deficits when injected into rodent brain and in mouse models of AD Aβ production is associated with impaired learning and/or recall. Here we examin...

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Hlavní autoři: Freir, Darragh B., Fedriani, Rocio, Scully, Darren, Smith, Imelda M., Selkoe, Dennis J., Walsh, Dominic M., Regan, Ciaran M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891223/
https://ncbi.nlm.nih.gov/pubmed/20097446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.01.001
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