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Transporters for L-glutamate: An update on their molecular pharmacology and pathological involvement

L-Glutamate (Glu) is the major excitatory neurotransmitter in the mammalian CNS and five types of high-affinity Glu transporters (EAAT1–5) have been identified. The transporters EAAT1 and EAAT2 in glial cells are responsible for the majority of Glu uptake while neuronal EAATs appear to have speciali...

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Detalhes bibliográficos
Main Authors: Beart, P M, O'Shea, R D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013845/
https://ncbi.nlm.nih.gov/pubmed/17088867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706949
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