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The Rho kinase inhibitor Fasudil up-regulates astrocytic glutamate transport subsequent to actin remodelling in murine cultured astrocytes

BACKGROUND AND PURPOSE: Glutamate transporters play a major role in maintaining brain homeostasis and the astrocytic transporters, EAAT1 and EAAT2, are functionally dominant. Astrocytic excitatory amino acid transporters (EAATs) play important roles in various neuropathologies wherein astrocytes und...

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Hlavní autoři: Lau, CL, O'Shea, RD, Broberg, BV, Bischof, L, Beart, PM
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101616/
https://ncbi.nlm.nih.gov/pubmed/21309758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01259.x
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