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Wound Contraction is Attenuated by Fasudil Inhibition of Rho-Kinase
BACKGROUND: Dermal scarring and scar contracture result in restriction of movement. There are no effective drugs to prevent scarring. RhoA and Rho Associated kinase (ROCK) have emerged as regulators of fibrosis and contracture. Fasudil, a ROCK inhibitor, has been demonstrated to have anti-fibrotic e...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205419/ https://ncbi.nlm.nih.gov/pubmed/22030503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0b013e31822b7352 |
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