Angiotensin II Stimulates Canonical TGFβ Signaling Pathway through Angiotensin Type 1 Receptor to Induce Granulation Tissue Contraction

Hypertrophic scar contraction (HSc) is caused by granulation tissue contraction propagated by myofibroblast and fibroblast migration and contractility. Identifying the stimulants that promote migration and contractility are key to mitigating HSc. AngiotensinII (AngII) promotes migration and contract...

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Detalhes bibliográficos
Publicado no:J Mol Med (Berl)
Main Authors: Ehanire, Tosan, Ren, Licheng, Bond, Jennifer, Medina, Manuel, Li, George, Bashirov, Latif, Chen, Lei, Kokosis, George, Ibrahim, Mohamed, Selim, Angelica, Blobe, Gerard C., Levinson, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334749/
https://ncbi.nlm.nih.gov/pubmed/25345602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1211-9
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