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System x(c)(-) cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS

System x(c)(-) is an amino acid antiporter that typically mediates the exchange of extracellular l-cystine and intracellular l-glutamate across the cellular plasma membrane. Studied in a variety of cell types, the import of l-cystine through this transporter is critical to glutathione production and...

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Detalhes bibliográficos
Main Authors: Bridges, Richard J, Natale, Nicholas R, Patel, Sarjubhai A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252963/
https://ncbi.nlm.nih.gov/pubmed/21564084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01480.x
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