The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration

Carbonic anhydrase IX is a hypoxia-induced transmembrane enzyme linked with solid tumors. It catalyzes the reversible hydration of CO(2) providing bicarbonate ions for intracellular neutralization and protons for extracellular acidosis, thereby supporting tumor cell survival and invasiveness. CA IX...

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Bibliographic Details
Main Authors: Csaderova, Lucia, Debreova, Michaela, Radvak, Peter, Stano, Matej, Vrestiakova, Magdalena, Kopacek, Juraj, Pastorekova, Silvia, Svastova, Eliska
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787331/
https://ncbi.nlm.nih.gov/pubmed/24101905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00271
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