The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration

Carbonic anhydrase IX is a hypoxia-induced transmembrane enzyme linked with solid tumors. It catalyzes the reversible hydration of CO(2) providing bicarbonate ions for intracellular neutralization and protons for extracellular acidosis, thereby supporting tumor cell survival and invasiveness. CA IX...

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Main Authors: Csaderova, Lucia, Debreova, Michaela, Radvak, Peter, Stano, Matej, Vrestiakova, Magdalena, Kopacek, Juraj, Pastorekova, Silvia, Svastova, Eliska
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787331/
https://ncbi.nlm.nih.gov/pubmed/24101905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00271
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