The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration

Carbonic anhydrase IX is a hypoxia-induced transmembrane enzyme linked with solid tumors. It catalyzes the reversible hydration of CO(2) providing bicarbonate ions for intracellular neutralization and protons for extracellular acidosis, thereby supporting tumor cell survival and invasiveness. CA IX...

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Hauptverfasser: Csaderova, Lucia, Debreova, Michaela, Radvak, Peter, Stano, Matej, Vrestiakova, Magdalena, Kopacek, Juraj, Pastorekova, Silvia, Svastova, Eliska
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787331/
https://ncbi.nlm.nih.gov/pubmed/24101905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00271
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