Carbonic Anhydrase IX Interacts with Bicarbonate Transporters in Lamellipodia and Increases Cell Migration via Its Catalytic Domain

Carbonic anhydrase IX (CA IX) is a hypoxia-induced cell surface enzyme expressed in solid tumors, and functionally involved in acidification of extracellular pH and destabilization of intercellular contacts. Since both extracellular acidosis and reduced cell adhesion facilitate invasion and metastas...

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Main Authors: Svastova, Eliska, Witarski, Wojciech, Csaderova, Lucia, Kosik, Ivan, Skvarkova, Lucia, Hulikova, Alzbeta, Zatovicova, Miriam, Barathova, Monika, Kopacek, Juraj, Pastorek, Jaromir, Pastorekova, Silvia
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Cell Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270993/
https://ncbi.nlm.nih.gov/pubmed/22170054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.286062
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