Carbonic Anhydrase IX Interacts with Bicarbonate Transporters in Lamellipodia and Increases Cell Migration via Its Catalytic Domain

Carbonic anhydrase IX (CA IX) is a hypoxia-induced cell surface enzyme expressed in solid tumors, and functionally involved in acidification of extracellular pH and destabilization of intercellular contacts. Since both extracellular acidosis and reduced cell adhesion facilitate invasion and metastas...

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Detalhes bibliográficos
Main Authors: Svastova, Eliska, Witarski, Wojciech, Csaderova, Lucia, Kosik, Ivan, Skvarkova, Lucia, Hulikova, Alzbeta, Zatovicova, Miriam, Barathova, Monika, Kopacek, Juraj, Pastorek, Jaromir, Pastorekova, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270993/
https://ncbi.nlm.nih.gov/pubmed/22170054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.286062
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