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Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors
Acidic tissue microenvironment contributes to tumor progression via multiple effects including the activation of angiogenic factors and proteases, reduced cell-cell adhesion, increased migration and invasion, etc. In addition, intratumoral acidosis can influence the uptake of anticancer drugs and mo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3884196/ https://ncbi.nlm.nih.gov/pubmed/24409151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00400 |
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