Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype

CA IX is a hypoxia-induced, cancer-associated carbonic anhydrase isoform with functional involvement in pH control and cell adhesion. Here we describe an alternative splicing variant of the CA9 mRNA, which does not contain exons 8–9 and is expressed in tumour cells independently of hypoxia. It is al...

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Detalhes bibliográficos
Main Authors: Barathova, M, Takacova, M, Holotnakova, T, Gibadulinova, A, Ohradanova, A, Zatovicova, M, Hulikova, A, Kopacek, J, Parkkila, S, Supuran, C T, Pastorekova, S, Pastorek, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359689/
https://ncbi.nlm.nih.gov/pubmed/18026188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604111
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