Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype

CA IX is a hypoxia-induced, cancer-associated carbonic anhydrase isoform with functional involvement in pH control and cell adhesion. Here we describe an alternative splicing variant of the CA9 mRNA, which does not contain exons 8–9 and is expressed in tumour cells independently of hypoxia. It is al...

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Détails bibliographiques
Auteurs principaux: Barathova, M, Takacova, M, Holotnakova, T, Gibadulinova, A, Ohradanova, A, Zatovicova, M, Hulikova, A, Kopacek, J, Parkkila, S, Supuran, C T, Pastorekova, S, Pastorek, J
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2008
Sujets:
Molecular Diagnostics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359689/
https://ncbi.nlm.nih.gov/pubmed/18026188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604111
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