The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration

Carbonic anhydrase IX is a hypoxia-induced transmembrane enzyme linked with solid tumors. It catalyzes the reversible hydration of CO(2) providing bicarbonate ions for intracellular neutralization and protons for extracellular acidosis, thereby supporting tumor cell survival and invasiveness. CA IX...

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Detalhes bibliográficos
Main Authors: Csaderova, Lucia, Debreova, Michaela, Radvak, Peter, Stano, Matej, Vrestiakova, Magdalena, Kopacek, Juraj, Pastorekova, Silvia, Svastova, Eliska
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787331/
https://ncbi.nlm.nih.gov/pubmed/24101905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00271
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