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Conformational Freedom in Tight Binding Enzymatic Transition State Analogues
Transition state analogues of bacterial 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidases (MTANs) disrupt quorum sensing pathways in Escherichia coli and Vibrio cholerae, demonstrating potential to limit pathogenicity without placing bacteria under intense selective pressure that leads to...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3786605/ https://ncbi.nlm.nih.gov/pubmed/23895500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp4030443 |
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