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On the Activation of Integrin αIIbβ3: Outside-in and Inside-out Pathways

Integrin αIIbβ3 is a member of the integrin family of transmembrane proteins present on the plasma membrane of platelets. Integrin αIIbβ3 is widely known to regulate the process of thrombosis via activation at its cytoplasmic side by talin and interaction with the soluble fibrinogen. It is also repo...

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Библиографические подробности
Главные авторы: Mehrbod, Mehrdad, Trisno, Stephen, Mofrad, Mohammad R.K.
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785890/
https://ncbi.nlm.nih.gov/pubmed/24047981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.055
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