The Antithrombotic Agent Pterostilbene Interferes with Integrin α(IIb)β(3)-Mediated Inside-Out and Outside-In Signals in Human Platelets

Platelets play a crucial role in the physiology of primary hemostasis and pathological processes such as arterial thrombosis; thus, developing a therapeutic target that prevents platelet activation can reduce arterial thrombosis. Pterostilbene (PTE) has remarkable pharmacological activities, includi...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Huang, Wei-Chieh, Lin, Kao-Chang, Hsia, Chih-Wei, Hsia, Chih-Hsuan, Chen, Ting-Yu, Bhavan, Periyakali Saravana, Sheu, Joen-Rong, Hou, Shaw-Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8037547/
https://ncbi.nlm.nih.gov/pubmed/33807403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22073643
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