Proline Substitution of Dimer Interface β-strand Residues as a Strategy for the Design of Functional Monomeric Proteins

Proteins that exist in monomer-dimer equilibrium can be found in all organisms ranging from bacteria to humans; this facilitates fine-tuning of activities from signaling to catalysis. However, studying the structural basis of monomer function that naturally exists in monomer-dimer equilibrium is cha...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Joseph, Prem Raj B., Poluri, Krishna Mohan, Gangavarapu, Pavani, Rajagopalan, Lavanya, Raghuwanshi, Sandeep, Richardson, Ricardo M., Garofalo, Roberto P., Rajarathnam, Krishna
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2013
Assuntos:
Proteins and Nucleic Acids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785864/
https://ncbi.nlm.nih.gov/pubmed/24048001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.08.008
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares