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Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation
Chaperone–usher pathway pili are a widespread family of extracellular, Gram-negative bacterial fibers with important roles in bacterial pathogenesis. Type 1 pili are important virulence factors in uropathogenic Escherichia coli (UPEC), which cause the majority of urinary tract infections (UTI). FimH...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785778/ https://ncbi.nlm.nih.gov/pubmed/24003161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315203110 |
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