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Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding
FimH, the type 1 pilus adhesin of uropathogenic Escherichia coli (UPEC), contains a receptor-binding domain with an acidic binding pocket specific for mannose. The fim operon, and thus type 1 pilus production, is under transcriptional control via phase variation of an invertible promoter element. Fi...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794649/ https://ncbi.nlm.nih.gov/pubmed/20018753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902179106 |
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