Positive selection identifies an in vivo role for FimH during urinary tract infection in addition to mannose binding

FimH, the type 1 pilus adhesin of uropathogenic Escherichia coli (UPEC), contains a receptor-binding domain with an acidic binding pocket specific for mannose. The fim operon, and thus type 1 pilus production, is under transcriptional control via phase variation of an invertible promoter element. Fi...

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Xehetasun bibliografikoak
Egile Nagusiak: Chen, Swaine L., Hung, Chia S., Pinkner, Jerome S., Walker, Jennifer N., Cusumano, Corinne K., Li, Zhaoli, Bouckaert, Julie, Gordon, Jeffrey I., Hultgren, Scott J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794649/
https://ncbi.nlm.nih.gov/pubmed/20018753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902179106
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