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Molecular Variations in Klebsiella pneumoniae and Escherichia coli FimH Affect Function and Pathogenesis in the Urinary Tract

Type 1 pili mediate binding, invasion, and biofilm formation of uropathogenic Escherichia coli (UPEC) in the host urothelium during urinary tract infection (UTI) via the adhesin FimH. In this study, we characterized the molecular basis of functional differences between FimH of the UPEC isolate UTI89...

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Bibliografiske detaljer
Main Authors: Rosen, David A., Pinkner, Jerome S., Walker, Jennifer N., Elam, Jennifer Stine, Jones, Jennifer M., Hultgren, Scott J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446687/
https://ncbi.nlm.nih.gov/pubmed/18474655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00340-08
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