Molecular Variations in Klebsiella pneumoniae and Escherichia coli FimH Affect Function and Pathogenesis in the Urinary Tract

Type 1 pili mediate binding, invasion, and biofilm formation of uropathogenic Escherichia coli (UPEC) in the host urothelium during urinary tract infection (UTI) via the adhesin FimH. In this study, we characterized the molecular basis of functional differences between FimH of the UPEC isolate UTI89...

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Autores principales: Rosen, David A., Pinkner, Jerome S., Walker, Jennifer N., Elam, Jennifer Stine, Jones, Jennifer M., Hultgren, Scott J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446687/
https://ncbi.nlm.nih.gov/pubmed/18474655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00340-08
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