Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters

ATP binding cassette (ABC) transmembrane efflux pumps such as P-glycoprotein (ABCB1), multidrug resistance protein 1 (ABCC1), and breast cancer resistance protein (ABCG2) play an important role in anti-cancer drug resistance. A large number of structurally and functionally diverse compounds act as s...

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Detalhes bibliográficos
Main Authors: Strouse, J. Jacob, Ivnitski-Steele, Irena, Waller, Anna, Young, Susan M., Perez, Dominique, Evangelisti, Annette M., Ursu, Oleg, Bologa, Cristian G., Carter, Mark B., Salas, Virginia M., Tegos, George, Larson, Richard S., Oprea, Tudor I., Edwards, Bruce S., Sklar, Larry A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785545/
https://ncbi.nlm.nih.gov/pubmed/23470221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.02.018
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