Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters

ATP binding cassette (ABC) transmembrane efflux pumps such as P-glycoprotein (ABCB1), multidrug resistance protein 1 (ABCC1), and breast cancer resistance protein (ABCG2) play an important role in anti-cancer drug resistance. A large number of structurally and functionally diverse compounds act as s...

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Main Authors: Strouse, J. Jacob, Ivnitski-Steele, Irena, Waller, Anna, Young, Susan M., Perez, Dominique, Evangelisti, Annette M., Ursu, Oleg, Bologa, Cristian G., Carter, Mark B., Salas, Virginia M., Tegos, George, Larson, Richard S., Oprea, Tudor I., Edwards, Bruce S., Sklar, Larry A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785545/
https://ncbi.nlm.nih.gov/pubmed/23470221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.02.018
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