Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget’s disease of bone

Paget’s disease is characterized by highly localized areas of increased osteoclast (OCL) activity. This suggests that the microenvironment in pagetic lesions is highly osteoclastogenic, or that OCL precursors in these lesions are hyperresponsive to osteoclastogenic factors (or both). To examine thes...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Menaa, Cheikh, Reddy, Sakamuri V., Kurihara, Noriyoshi, Maeda, Hidefumi, Anderson, Dirk, Cundy, Tim, Cornish, Jillian, Singer, Frederick R., Bruder, Jan M., Roodman, G. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC378510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10862799/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9133
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